| Product Name/Description | No. of Reactions* | Product Code |
| BRCA Complete™ (For Illumina® Platforms) | Up to 40 | BRCA-NGS |
*Includes all controls
EntroGen BRCA Complete™ is a complete NGS solution from DNA to interpreting sequencing data that detects germline and somatic BRCA1/BRCA2 mutations with comprehensive coverage, specificity, and high sensitivity. BRCA Complete™ is compatible with blood, fresh frozen, and formalin fixed paraffin embedded (FFPE) samples. Allele dropouts and off-target reads are reduced through a tiled amplicon PCR approach coupled with a high fidelity polymerase for target enrichment. Reagents for library preparation and clean-up are included in BRCA Complete™ as well as a local, user-friendly software designed to reduce the bioinformatics burden on the end-user by calling clinically relevant mutations directly from VCF files. Sample and library quality control assays (DNA Fragmentation Quantification assay, Library Quantification Kit for Illumina®) are available to ensure high quality data without the need for repeat sequencing.
The panel offers all reagents necessary for target enrichment and library construction for Illumina® platforms from DNA isolated from patient samples. Sample quality assessment assays (DNA Fragmentation Quantification assay, Library Quantification Kit for Illumina®) are available to ensure samples and sequencing reagents are not wasted. The complimentary software queries three independent databases to call clinically relevant variants based on Illumina® output reports.
Equipment & Materials:BRCA Complete™ requires the following equipment:
The kit includes reagents for:
The reagents in the kit are to prepare sequencing libraries for up to 40 samples.
USA: BRCA Complete™ is provided for research use only (RUO). Not for use in diagnostic procedures.
Europe: BRCA Complete™ is provided for research (RUO) and diagnostic (CE-IVD) purposes.